Gova/b alloantigen system on human platelets

Gova/b alloantigen system on human platelets.

In this report we describe a platelet alloantigen system that is carried on a novel platelet protein of 175 Kd. Antisera against the two alleles (Gova/Govb) were found in two patients who had received large numbers of platelet transfusions. The anti-Gov alloantibodies could not be detected using a whole platelet solid phase enzyme immunoassay, or by a platelet glycoprotein capture enzyme immuno...

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The Bra/Brb alloantigen system on human platelets.

Anti-Bra was first identified in four cases of neonatal alloimmune thrombocytopenia (NAIT). The antigen Bra is localized on the glycoprotein Ia/IIa complex of platelets. Anti-Bra can best be detected by a glycoprotein-specific immunoassay using monoclonal antibodies for antigen immobilization (MAIPA assay) and radioimmunoprecipitation (RIP). Recently, we have identified sera from two polytransf...

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The Bra/Br” Alloantigen System on Human Platelets

Anti-Br was first identified in four cases of neonatal alloimmune thrombocytopenia (NAIT). The antigen Br is localized on the glycoprotein la/Ila complex of platelets. Anti-Br’ can best be detected by a glycoprotein-specific immunoassay using monoclonal antibodies for antigen immobilization (MAIPA assay) and radioimmunoprecipitation (RIP). Recently, we have identified sera from two polytransfus...

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The Bra/Br” Alloantigen System on Human Platelets

Anti-Br was first identified in four cases of neonatal alloimmune thrombocytopenia (NAIT). The antigen Br is localized on the glycoprotein la/Ila complex of platelets. Anti-Br’ can best be detected by a glycoprotein-specific immunoassay using monoclonal antibodies for antigen immobilization (MAIPA assay) and radioimmunoprecipitation (RIP). Recently, we have identified sera from two polytransfus...

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The Bra/Br” Alloantigen System on Human Platelets

Anti-Br was first identified in four cases of neonatal alloimmune thrombocytopenia (NAIT). The antigen Br is localized on the glycoprotein la/Ila complex of platelets. Anti-Br’ can best be detected by a glycoprotein-specific immunoassay using monoclonal antibodies for antigen immobilization (MAIPA assay) and radioimmunoprecipitation (RIP). Recently, we have identified sera from two polytransfus...

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Gova/b alloantigen system on human platelets

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